High Serum Advanced Glycation End Products Are Associated with Decreased Insulin Secretion in Patients with Type 2 Diabetes: A Brief Report
Objective.Advanced glycation end products (AGEs) are important in the pathophysiology of type 2 diabetes mellitus (T2DM).They directly cause insulin secretory defects in animal read more and cell culture models and may promote insulin resistance in nondiabetic subjects.We have developed a highly sensitive liquid chromatography-tandem mass spectrome